In Sumerian mythology and later for Assyrians and Babylonians, Anu (also An; (from Sumerian *An = sky, heaven)) was a sky-god, the god of heaven, lord of constellations, king of gods, spirits and demons, and dwelt in the highest heavenly regions. It was believed that he had the power to judge those who had committed crimes, and that he had created the stars as soldiers to destroy the wicked. His attribute was the royal tiara, most times decorated with two pairs of bull horns. In art he was sometimes depicted as a jackal. Some compare this to the idea that he is the grandfather of all demons, because he is the father of tiamat.

He had several consorts, the foremost being Ki (earth), Nammu, and Uras. By Ki he was the father of, among others, the Annuna gods, and Tiamat. By Nammu he was the father of, among others, Enki and Ningikuga. By Uras he was the father of Nin'insinna. According to legends, heaven and earth were once inseparable until An and Ki bore Enlil, god of the the air, who cleaved heaven and earth in two. An and Ki were, in some texts, identified as brother and sister being the children of Anshar and Kishar. Ki later developed into the Akkadian goddess Antu.

He was one of the oldest gods in the Sumerian pantheon, and part of a triad including Enlil, god of the sky and Enki, god of water. He was called Anu by the Akkadians, rulers of Mesopotamia after the conquest of Sumer in 2334 BCE by King Sargon of Akkad. By virtue of being the first figure in a triad consisting of Anu, Bel and Ea, Anu came to be regarded as the father and at first, king of the gods. Anu is so prominently associated with the E-anna temple in the city of Uruk (biblical Erech) in southern Babylonia that there are good reasons for believing this place to have been the original seat of the Anu cult. If this be correct, then the goddess Inanna (or Ishtar) of Uruk may at one time have been his consort.

The name of this god signifies the "high one" and he was probably a god of the atmospheric region above the earth—perhaps a storm god like Adad. However this may be, already in the old-Babylonian period, i.e. before Hammurabi, Anu was regarded as the god of the heavens and his name in Sumerian in fact is synonymous with the heavens, so that in some cases it is doubtful whether, under the term, the god or the heavens is meant. It would seem from this that the grouping of the divine powers recognized in the universe into a triad symbolizing the three divisions, heavens, earth and the watery-deep, was a process of thought which had taken place before the third millennium.

The doctrine once established remained an inherent part of the Babylonian-Assyrian religion and led to the more or less complete disassociation of the three gods constituting the triad from their original local limitations. An intermediate step between Anu viewed as the local deity of Uruk, Enlil as the god of Nippur, and Ea as the god of Eridu is represented by the prominence which each one of the centres associated with the three deities in question must have acquired, and which led to each one absorbing the qualities of other gods so as to give them a controlling position in an organized pantheon. For Nippur we have the direct evidence that its chief deity, En-lil, was once regarded as the head of the Sumerian pantheon. The sanctity and, therefore, the importance of Eridu remained a fixed tradition in the minds of the people to the latest days, and analogy therefore justifies the conclusion that Anu was likewise worshipped in a centre which had acquired great prominence.

The summing-up of divine powers manifested in the universe in a threefold division represents an outcome of speculation in the schools attached to the temples of Babylonia, but the selection of Anu, Enlil (and later Marduk) and Ea for the three representatives of the three spheres recognized, is due to the importance which, for one reason or the other, the centres in which Anu, Enlil and Ea were worshipped had acquired in the popular mind. Each of the three must have been regarded in his centre as the most important member in a larger or smaller group, so that their union in a triad marks also the combination of the three distinctive pantheons into a harmonious whole.

In the astral theology of Babylonia and Assyria, Anu, Enlil and Ea became the three zones of the ecliptic, the northern, middle and southern zone respectively. The purely theoretical character of Anu is thus still further emphasized, and in the annals and votive inscriptions as well as in the incantations and hymns, he is rarely introduced as an active force to whom a personal appeal can be made. His name becomes little more than a synonym for the heavens in general and even his title as king or father of the gods has little of the personal element in it. A consort Antum (or as some scholars prefer to read, Anatum) is assigned to him, on the theory that every deity must have a female associate, but Antum is a purely artificial product—a lifeless symbol playing even less of a part in what may be called the active pantheon than Anu.

In Hurrian mythology, Anu was the progenitor of all gods. His son Kumarbi bit off his genitals and spat out three deities, one of whom, Teshub, later deposed Kumarbi.

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